Pages tagged with DNA polymerase eta

POLH gene

The POLH gene is 40kbp long and contains 11 exons, that generate a 2432bp long mRNA.[1] Unlike in mice, there is no higher incidence of skin cancer...

Cyclobutane pyrimidine dimers (CPDs)

CPDs can form when two pyrimidine nucleotides (C or T) next to each other in the DNA are exposed to UV-light. CPD is the most abundant form of...

Translesion Synthesis (TLS)

Lesions, or DNA damage, can lead to complications during the replication process. Some proteins, like DNA polymerases that can bypass damage in the...